NAD+ / MOTS-c / 5-Amino-1MQ Blend – 120mg (100mg / 10mg / 10mg)

NAD+ / MOTS-c / 5-Amino-1MQ Peptide Blend Description

The BioLongevity Labs NAD+/MOTS-c/5-Amino-1MQ Blend unites three distinct compounds that converge on cellular energy, mitochondrial function, and metabolic regulation:

• NAD+ (100 mg) replenishes the central redox cofactor required for metabolism, DNA repair, and sirtuin activation [1][2][3].
• MOTS-c (10 mg) is a mitochondria-derived peptide that activates AMPK, regulates nuclear gene expression under metabolic stress, and enhances insulin sensitivity [4][5][6].
• 5-Amino-1MQ (10 mg) inhibits NNMT, raising NAD+ levels while modulating histone methylation and fat metabolism pathways [7][8][9].

Together, their mechanisms are designed to:

• Enhance mitochondrial and cellular energy balance by restoring NAD+ pools and activating AMPK [1][4][7].
• Improve metabolic health by reducing adiposity, sustaining muscle function, and optimizing glucose regulation [2][5][8].
• Support cognitive and longevity research through effects on neuroinflammation, oxidative stress, and cellular senescence [3][6][9].

Peptide Structures

NAD+ (Nicotinamide Adenine Dinucleotide)

• Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
• Molecular Weight: 663.43 g/mol
• PubChem CID: 925
• CAS Number: 53-84-9
• Synonyms: β-Nicotinamide adenine dinucleotide, DPN, Coenzyme I, Diphosphopyridine nucleotide

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c)

• Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
• Molecular Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂
• Molecular Weight: 2174.6 g/mol
• PubChem SID: 255386757
• CAS Number: 1627580-64-6
• Synonyms: Human MOTS-c, UNII-A5CV6JFB78, MOTS-c trifluoroacetate salt

5-Amino-1MQ (5-Amino-1-methylquinolinium)

• Molecular Formula: C₁₀H₁₁N₂
• Molecular Weight: 159.21 g/mol
• PubChem CID: 950107
• CAS Number: —
• Synonyms: 5-amino-1-methylquinolinium, SCHEMBL6403148, CHEMBL4116828, ZMJBCEIHNOWCMC-UHFFFAOYSA-O, STL196667

This synergistic triad provides a unique investigational platform for metabolism, neuroprotection, and healthy aging research.

Blend Structure

Ingredient	Dose (per capsule)	Key Actions
NAD+	100 mg	Cofactor in redox metabolism; activates sirtuins & AMPK; supports DNA repair & mitochondrial biogenesis [1][2][3]
MOTS-c	10 mg	Mitochondria-encoded peptide; AMPK activation; improves insulin sensitivity; prevents metabolic dysfunction [4][5][6]
5-Amino-1MQ	10 mg	NNMT inhibitor; ↑NAD+; ↓adiposity; epigenetic modulation; metabolic & oncology research [7][8][9]

Research Areas

• Cellular Energy & Mitochondrial Function
• Metabolic Regulation & Obesity Research
• Muscle Preservation & Physical Performance
• Neuroprotection & Cognitive Function
• Longevity & Anti-Aging Mechanisms
• Preclinical Cancer Research